影響發酵罐設備發酵的因素有哪些？

影響發酵罐設(she)備發酵過程(cheng)變化(hua)的(de)(de)參(can)(can)數(shu)(shu)(shu)(shu)(shu)可以(yi)分為兩類(lei)：一類(lei)是可以(yi)直(zhi)接采用(yong)(yong)特定的(de)(de)傳感器檢(jian)測(ce)(ce)的(de)(de)參(can)(can)數(shu)(shu)(shu)(shu)(shu)。它們囊括反(fan)映(ying)物(wu)理情況與化(hua)學狀況更改的(de)(de)參(can)(can)數(shu)(shu)(shu)(shu)(shu)，網羅(luo)細胞(bao)生長速率(lv)、出(chu)產物(wu)合成(cheng)速率(lv)和(he)呼吸明日等(deng)。借助于電腦(nao)合計和(he)特定的(de)(de)數(shu)(shu)(shu)(shu)(shu)學模子才智獲取(qu)。另外一類(lei)是至今尚(shang)難于用(yong)(yong)傳感器來檢(jian)測(ce)(ce)的(de)(de)參(can)(can)數(shu)(shu)(shu)(shu)(shu)，如溫(wen)(wen)度、壓力、攪拌功率(lv)、轉速、泡沫、發酵液(ye)粘(zhan)度、濁度、pH、離子濃(nong)(nong)度、溶(rong)解氧(yang)(yang)、基質濃(nong)(nong)度等(deng)，因而這種參(can)(can)數(shu)(shu)(shu)(shu)(shu)被喻為間接參(can)(can)數(shu)(shu)(shu)(shu)(shu)。這些(xie)參(can)(can)數(shu)(shu)(shu)(shu)(shu)需要按(an)照一些(xie)直(zhi)接檢(jian)測(ce)(ce)出(chu)來的(de)(de)參(can)(can)數(shu)(shu)(shu)(shu)(shu)，稱為直(zhi)接參(can)(can)數(shu)(shu)(shu)(shu)(shu)。上述參(can)(can)數(shu)(shu)(shu)(shu)(shu)中，對發酵過程(cheng)影響較大的(de)(de)有(you)溫(wen)(wen)度、pH、溶(rong)解氧(yang)(yang)濃(nong)(nong)度等(deng)。

影響發酵罐設(she)備發酵的因素如何控(kong)制：

理(li)論上，整(zheng)(zheng)個發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)過(guo)程中(zhong)(zhong)不應只選一個培養溫(wen)度。在生長階段(duan)，應選擇適(shi)合生長溫(wen)度，在產(chan)(chan)物(wu)分泌階段(duan)，應選擇適(shi)合生產(chan)(chan)溫(wen)度。但實(shi)際(ji)生產(chan)(chan)中(zhong)(zhong)，由于發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)液的(de)(de)(de)體積很(hen)大，升降溫(wen)度都比(bi)較困難(nan)，所以在整(zheng)(zheng)個發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)過(guo)程中(zhong)(zhong)，往往采用一個比(bi)較適(shi)合的(de)(de)(de)培養溫(wen)度，使得到的(de)(de)(de)產(chan)(chan)物(wu)產(chan)(chan)量很(hen)高，或(huo)者在可能的(de)(de)(de)條(tiao)件下進行(xing)適(shi)當(dang)的(de)(de)(de)調整(zheng)(zheng)。發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)溫(wen)度可通(tong)(tong)過(guo)溫(wen)度計或(huo)自動(dong)記錄(lu)儀表進行(xing)檢測，通(tong)(tong)過(guo)向發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)罐的(de)(de)(de)夾(jia)套(tao)或(huo)蛇(she)(she)形管中(zhong)(zhong)通(tong)(tong)人冷(leng)水(shui)、熱(re)水(shui)或(huo)蒸汽進行(xing)調節。因發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)中(zhong)(zhong)釋(shi)放了(le)大量的(de)(de)(de)發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)熱(re)，在這種情況下通(tong)(tong)常還需要加以冷(leng)下來，利用自動(dong)控制或(huo)手(shou)動(dong)調整(zheng)(zheng)的(de)(de)(de)閥門(men)，將冷(leng)掉水(shui)通(tong)(tong)人夾(jia)套(tao)或(huo)蛇(she)(she)形管中(zhong)(zhong)，通(tong)(tong)過(guo)熱(re)交換來降溫(wen)，保持恒溫(wen)發(fa)(fa)酵(jiao)(jiao)(jiao)(jiao)。